Persistent subcutaneous nodules after immunotherapy injections for allergic asthma

Güler Özden, Müge; Kefeli, Mehmet; Aydın, Fatma; Şentürk, Nilgün; Canturk, Tayyar; Turanli, Ahmet

doi:10.1111/j.1600-0560.2008.01152.x

Persistent subcutaneous nodules after immunotherapy injections for allergic asthma

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Güler Özden M., Kefeli M., Aydın F., Şentürk N., Canturk T., Turanli A. Y.

JOURNAL OF CUTANEOUS PATHOLOGY, vol.36, no.7, pp.812-814, 2009 (SCI-Expanded)

Publication Type: Article / Article
Volume: 36 Issue: 7
Publication Date: 2009
Doi Number: 10.1111/j.1600-0560.2008.01152.x
Journal Name: JOURNAL OF CUTANEOUS PATHOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.812-814
Ondokuz Mayıs University Affiliated: Yes

Abstract

Adverse effects of desensitization injections mostly consist of local transient reactions. Rarely, persistent subcutaneous nodular lesions may also develop at the site of injection. These reactions have been attributed to the vaccines containing aluminium hydroxide. Aluminium hydroxide is used as an adjuvant in vaccines and hyposensitization solutions. We describe a patient who presented persistent, itchy subcutaneous nodules as a local reaction to allergen immunotherapy for the treatment of allergic asthma.