Phytochemical studies and antibacterial activity of the aerial parts of physospermum verticillatum

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Boulacel I., Djarri L., Azzouzi S., Medjroubi K., Demirtas İ., Laouer H., ...Daha Fazla

Bangladesh Journal of Pharmacology, cilt.12, sa.2, ss.107-112, 2017 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3329/bjp.v12i2.29668
  • Dergi Adı: Bangladesh Journal of Pharmacology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.107-112
  • Anahtar Kelimeler: Antibacterial, Physospermum verticillatum
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Ondokuz Mayıs Üniversitesi Adresli: Hayır

Özet

In this study, we focused on the isolation and identification of the main compounds, triterpene, sterol, phenolic and fatty acid from the aerial parts of Physospermum verticillatum, which has not been previously reported. Dichloro-methane, ethyl acetate and n-butanol extracts led to the isolation of ß-amyrin (1), 3,11-dihydroxy-12-oleanene (2), pentadecanoic acid (3), spina-sterol (4), spinasterol-3-O-ß-D-glucopyranoside (5) and saikochromic acid (6). These compounds were determined by means of the combined systems with high resolution tandem mass spectrometry (HPLC-TOF/MS), 1D NMR (1 H NMR,13C NMR) and 2D NMR(COSY, HSQC and HMBC). Further, the extracts demonstrated significant antibacterial activity.