Red Cell Distribution Width and Mean Platelet Volume in Amyloidosis
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, vol.20, no.3, pp.334-337, 2014 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 20 Issue: 3
- Publication Date: 2014
- Doi Number: 10.1177/1076029612462761
- Journal Name: CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.334-337
- Keywords: amyloidosis, red cell distribution width, mean platelet volume, HEART-FAILURE, BLOOD, DISEASE, MARKER, HYPERTENSION, INFLAMMATION, RISK
- Ondokuz Mayıs University Affiliated: Yes
Abstract
We aimed to determine whether red cell distribution width (RDW) and mean platelet volume (MPV) values differ between patients with reactive amyloid A (AA) amyloidosis due to chronic inflammatory disease and in healthy participants. In this study, 33 patients with AA amyloidosis and 40 age- and sex-matched healthy controls were enrolled. Erythrocyte sedimentation rate (ESR), RDW, platelet count (PLT), and MPV levels were retrospectively obtained from our computerized patient database. We found RDW, ESR, and PLT levels to be significantly higher in patients with AA amyloidosis compared with the controls (P < .0001). Mean platelet volume was significantly lower in patients with amyloidosis (P < .0001). Inflammatory diseases such as AA amyloidosis may demonstrate low MPV and high RDW levels.