Evaluation of Antinociceptive and Neurotoxic Effects of Intrathecal Dexmedetomidine in Rats
BALKAN MEDICAL JOURNAL, cilt.29, sa.4, ss.354-357, 2012 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 29 Sayı: 4
- Basım Tarihi: 2012
- Doi Numarası: 10.5152/balkanmedj.2012.034
- Dergi Adı: BALKAN MEDICAL JOURNAL
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.354-357
- Anahtar Kelimeler: Dexmedetomidine, intrathecal, neurotoxicity, histopathology, rat, SPINAL-CORD, CLONIDINE, ANTAGONIST, AGONIST, BUPIVACAINE, ANALGESIA, EFFICACY, PAIN
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ondokuz Mayıs Üniversitesi Adresli: Evet
Özet
Objective: Dexmedetomidine has been reported to produce analgesia after intrathecal administration. In the present study the alpha 2-adrenoceptor agonist dexmedetomidine was evaluated for its potential spinal neurotoxic effects.