SAA1 alpha/alpha alleles in amyloidosis
JOURNAL OF NEPHROLOGY, vol.19, no.2, pp.189-191, 2006 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 19 Issue: 2
- Publication Date: 2006
- Journal Name: JOURNAL OF NEPHROLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.189-191
- Keywords: SAA1 allele, amyloidosis, familial Mediterranean fever, FAMILIAL MEDITERRANEAN FEVER, SYSTEMIC AA-AMYLOIDOSIS, SECONDARY, RISK, GENOTYPES, MEFV, LOCI
- Ondokuz Mayıs University Affiliated: Yes
Abstract
Background. Amyloidosis, mainly AA type, is one of the common diseases in nephrology clinics in Turkey. AA type amyloidosis is a complication of various chronic infections or inflammatory diseases such as familial Mediterranean fever (IMF), rheumatoid arthritis (RA), tuberculosis and bronchiectasis. A controversy exists in the literature regarding the relationship between SAA1 genotypes and AA type amyloidosis. This study aimed to investigate SAA1 gene polymorphism in different patient groups: 1) amyloidosis, 2) FMF and 3) healthy controls.