Akademik Veri Yönetim Sistemi
Sunum, ss.195-203, 2006
Innate component of immunity is a skilful system that senses invading microbial pathogens and integrates to adaptive immunity by Toll-like receptors (TLRs). Another function of TLRs is to work in sterile inflammation to ligands derived from damaged cells, which are not usually present in the extracellular environment. Thus, TLRs have very important interferences in the pathogenesis of inflammatory and immune diseases. The discovery of TLRs has transformed our approach to immunology and related diseases.