Charcoal hemoperfusion in bupropion overdose

Akdemir H. U., Çalışkan F., Duran L., Katı C., Gungorer B., Ocak M.

JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, vol.113, no.10, pp.754-755, 2014 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 113 Issue: 10
  • Publication Date: 2014
  • Doi Number: 10.1016/j.jfma.2014.01.019
  • Journal Name: JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.754-755
  • Keywords: bupropion, hemoperfusion, overdose, seizure
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Bupropion is a relatively new and popular medication for depression, with seizures as its major side effect. In the literature, there are insufficient data about hemodialysis following bupropion overdose. A 23-year-old female patient was brought to our emergency department with acute change in mental status and seizure after deliberate self-poisoning with approximately 25-30 tablets of bupropion hydrochloride. Her Glasgow coma scale score was 8/15. The patient underwent hemodialysis about 4 hours later. After 4 hours of extracorporeal treatment, she became conscious and was extubated. We present a case of full recovery after charcoal hemoperfusion following a bupropion overdose. Copyright (C) 2014, Elsevier Taiwan LLC & Formosan Medical Association. All rights reserved.