Effects of Subthalamic Nucleus Deep Brain Stimulation Surgery on Voice and Formant Frequencies of Vowels in Turkish

Yaşar Ö., Ozturk S., Kemal Ö., Kocabıçak E.

TURKISH NEUROSURGERY, cilt.32, sa.5, ss.764-772, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 5
  • Basım Tarihi: 2022
  • Doi Numarası: 10.5137/1019-5149.jtn.36134-21.2
  • Dergi Adı: TURKISH NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.764-772
  • Anahtar Kelimeler: Acoustic, Deep brain stimulation, Parkinson?s disease, Subthalamic nucleus, voice, PARKINSONS-DISEASE, MULTIPLE-SCLEROSIS, SPEECH, DISORDERS
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

AIM: To investigate the effects of deep brain stimulation (DBS) of the subthalamic nucleus (STN) on acoustic characteristics of voice production in Turkish patients with Parkinson's disease (PD). MATERIAL and METHODS: This study recruited 20 patients diagnosed with PD. Voice samples were recorded under the "stimulation on" and "stimulation off" conditions of STN-DBS. Acoustic recordings of the patients were made during the production of vowels /a/, /o/, and /i/ and repetition of the syllables /pa/-/ta/-/ka/. Acoustic analyses were performed using Praat.RESULTS: A significant difference in the parameters was observed among groups for vowels. A positive significant difference was observed between preoperative med-on and postoperative med-on/stim-on groups for /a/ and the postoperative med-on/ stim-on and postoperative med-on/stim-off groups for /o/ and /i/ for frequency perturbation (jitter) and noise-to-harmonics ratio. No significant difference was noted between the preoperative med-on and postoperative med-on/stim-off groups for any vowels. CONCLUSION: STN-DBS surgery has an acute positive effect on voice. Studies on formant frequency analysis in STN-DBS may be expanded with both articulation and intelligibility tests to enable us to combine patient abilities in various perspectives and to obtain precise results.