Effects of Subthalamic Nucleus Deep Brain Stimulation Surgery on Voice and Formant Frequencies of Vowels in Turkish
TURKISH NEUROSURGERY, vol.32, no.5, pp.764-772, 2022 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 32 Issue: 5
- Publication Date: 2022
- Doi Number: 10.5137/1019-5149.jtn.36134-21.2
- Journal Name: TURKISH NEUROSURGERY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
- Page Numbers: pp.764-772
- Keywords: Acoustic, Deep brain stimulation, Parkinson?s disease, Subthalamic nucleus, voice, PARKINSONS-DISEASE, MULTIPLE-SCLEROSIS, SPEECH, DISORDERS
- Ondokuz Mayıs University Affiliated: Yes
Abstract
AIM: To investigate the effects of deep brain stimulation (DBS) of the subthalamic nucleus (STN) on acoustic characteristics of voice production in Turkish patients with Parkinson's disease (PD). MATERIAL and METHODS: This study recruited 20 patients diagnosed with PD. Voice samples were recorded under the "stimulation on" and "stimulation off" conditions of STN-DBS. Acoustic recordings of the patients were made during the production of vowels /a/, /o/, and /i/ and repetition of the syllables /pa/-/ta/-/ka/. Acoustic analyses were performed using Praat.RESULTS: A significant difference in the parameters was observed among groups for vowels. A positive significant difference was observed between preoperative med-on and postoperative med-on/stim-on groups for /a/ and the postoperative med-on/ stim-on and postoperative med-on/stim-off groups for /o/ and /i/ for frequency perturbation (jitter) and noise-to-harmonics ratio. No significant difference was noted between the preoperative med-on and postoperative med-on/stim-off groups for any vowels. CONCLUSION: STN-DBS surgery has an acute positive effect on voice. Studies on formant frequency analysis in STN-DBS may be expanded with both articulation and intelligibility tests to enable us to combine patient abilities in various perspectives and to obtain precise results.