Granulocyte-macrophage-colony-stimulating factor in the treatment of neonatal glossitis due to pseudomonas infection Yenidoǧanda psödomonas glossitinin tedavisinde topikal granülosit-makrofaj-koloni stimülan faktör kullanimi
Cocuk Sagligi ve Hastaliklari Dergisi, vol.46, no.4, pp.281-283, 2003 (Scopus)
- Publication Type: Article / Article
- Volume: 46 Issue: 4
- Publication Date: 2003
- Journal Name: Cocuk Sagligi ve Hastaliklari Dergisi
- Journal Indexes: Scopus
- Page Numbers: pp.281-283
- Keywords: Glossitis, Granulocyte-macrophage-colony-stimulating factor, Newborn
- Ondokuz Mayıs University Affiliated: No
Abstract
Granulocyte-macrophage-colony-stimulating factor (GM-CSF) not only influences the proliferation and differentiation of stem cells but also regulates other cells mediating inflammatory reactions and immune response. Accordingly, rhGM-CSF mouthwashes have been used for some years for the treatment of oral glossitis caused by radio- or chemotherapy. Based on these data we used topical rhGM-CSF in addition to parenteral antibiotic treatment in a preterm infant with glossitis due to Pseudomonas aeruginosa. We observed a quick healing of the tongue without any side effects.