Effect of temperature and some common metals on the stability of volatile anaesthetic-Entonox mixtures
Journal of Chromatography B: Biomedical Applications, cilt.709, sa.2, ss.217-223, 1998 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 709 Sayı: 2
- Basım Tarihi: 1998
- Doi Numarası: 10.1016/s0378-4347(98)00072-3
- Dergi Adı: Journal of Chromatography B: Biomedical Applications
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.217-223
- Anahtar Kelimeler: Enflurane, Entonox, Halothane, Isoflurane
- Ondokuz Mayıs Üniversitesi Adresli: Evet
Özet
Thermal stability of pressurised ready-to-use volatile liquid anaesthetic mixtures (halothane, isoflurane and enflurane) in Entonox (commercially available premixed 50% N2O, 50% O2 mixture) were investigated at temperatures of 20, 258, 400, 503 and 602°C on glass, stainless steel, copper and aluminium by gas chromatography and GC-MS. It was found that most of the decomposition products formed were halogenated compounds and the observed thermal stabilities in glass, stainless steel and copper allowed a thermal treatment up to 250°C without any decomposition problem. Aluminium was found to be the most effective metal at causing decomposition of the anaesthetic mixtures even at lower temperatures.