Neuroprotective Effects of Methylprednisolone and Hypothermia after Experimental Spinal Cord Injury: A Histopathological and Stereological Study

Unal B., Kaplan S., Odaci E., Aslan H., Aksak S., Unal D., ...More

EURASIAN JOURNAL OF MEDICINE, vol.41, no.3, pp.169-174, 2009 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 3
  • Publication Date: 2009
  • Journal Name: EURASIAN JOURNAL OF MEDICINE
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.169-174
  • Keywords: Cavalieri principle, Hypothermia, Experimental spinal cord injury, Methylprednisolone, Stereology
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Objective: Spinal cord injury is a common trauma among severe accidents in which the spinal cord has been severed; intravenous methylprednisolone and hypothermia are widely used in the treatment of traumatic spinal cord injuries. However, no common consensus has been reached on therapeutic approaches to prevent and reduce disability caused by spinal cord injuries. In this study, the efficacy of methylprednisolone and hypothermia treatments after experimental spinal cord injury made by dynamic weight-drop model in rabbits was investigated.