Can empirical hypertonic saline or sodium bicarbonate treatment prevent the development of cardiotoxicity during serious amitriptyline poisoning? Experimental research

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Paksu M. S., Zengin H., Ilkaya F., Paksu S., Guzel H., Ucar D., ...Daha Fazla

CARDIOVASCULAR JOURNAL OF AFRICA, cilt.26, sa.3, ss.134-139, 2015 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 26 Sayı: 3
• Basım Tarihi: 2015
• Doi Numarası: 10.5830/cvja-2015-014
• Dergi Adı: CARDIOVASCULAR JOURNAL OF AFRICA
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.134-139
• Anahtar Kelimeler: amitriptyline, poisoning, cardiotoxicity, sodium bicarbonate, hypertonic saline, TRICYCLIC ANTIDEPRESSANT OVERDOSE, INDUCED CARDIOVASCULAR TOXICITY, CHARCOAL HEMOPERFUSION, INTOXICATION, CHILDREN, RATS, HYPERVENTILATION, HYPONATREMIA, HYPOTENSION, EMERGENCY
• Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
• Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Objective: The aim of this experimental study was to investigate whether hypertonic saline or sodium bicarbonate administration prevented the development of cardiotoxicity in rats that received toxic doses of amitriptyline.