Can empirical hypertonic saline or sodium bicarbonate treatment prevent the development of cardiotoxicity during serious amitriptyline poisoning? Experimental research
CARDIOVASCULAR JOURNAL OF AFRICA, vol.26, no.3, pp.134-139, 2015 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 26 Issue: 3
- Publication Date: 2015
- Doi Number: 10.5830/cvja-2015-014
- Journal Name: CARDIOVASCULAR JOURNAL OF AFRICA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.134-139
- Keywords: amitriptyline, poisoning, cardiotoxicity, sodium bicarbonate, hypertonic saline, TRICYCLIC ANTIDEPRESSANT OVERDOSE, INDUCED CARDIOVASCULAR TOXICITY, CHARCOAL HEMOPERFUSION, INTOXICATION, CHILDREN, RATS, HYPERVENTILATION, HYPONATREMIA, HYPOTENSION, EMERGENCY
- Open Archive Collection: AVESIS Open Access Collection
- Ondokuz Mayıs University Affiliated: Yes
Abstract
Objective: The aim of this experimental study was to investigate whether hypertonic saline or sodium bicarbonate administration prevented the development of cardiotoxicity in rats that received toxic doses of amitriptyline.