Investigation of the 8-hydroxy-2 '-deoxyguanosine, total antioxidant and nitric oxide levels of serum in dogs infected with Babesia vogeli
VETERINARY PARASITOLOGY, vol.204, no.3-4, pp.388-391, 2014 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 204 Issue: 3-4
- Publication Date: 2014
- Doi Number: 10.1016/j.vetpar.2014.05.002
- Journal Name: VETERINARY PARASITOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.388-391
- Keywords: Babesia vogeli, Oxidative stress, Nitric oxide, 8-Hydroxy-2 '-deoxyguanosine, Total antioxidant capacity, OXIDATIVE STRESS, LIPID-PEROXIDATION, DISRUPTION, PLASMA, ASSAY
- Ondokuz Mayıs University Affiliated: Yes
Abstract
Oxidative stress was defined as corruption of balance between oxidant-antioxidant states in favor of oxidants. In this study, it was aimed to determine oxidative stress in naturally infected dogs with Babesia vogeli. The 8-hydroxy-2'-deoxyguanosine (8-OHdG), nitric oxide (NO) and total antioxidant capacity (TAC) levels in the sera were analyzed by ELISA. 8-OHdG levels increased in B. vogeli infected dogs compared to control group (P < 0.05). Also, NO levels increased while TOC levels decreased in B. vogeli infected dogs but these variations were not found as statistically important (P > 0.05). (C) 2014 Elsevier B.V. All rights reserved.