Investigation of the 8-hydroxy-2 '-deoxyguanosine, total antioxidant and nitric oxide levels of serum in dogs infected with Babesia vogeli

Çiftci G., URAL K., AYSUL N., Çenesiz S., Güzel M., Pekmezci D., ...More

VETERINARY PARASITOLOGY, vol.204, no.3-4, pp.388-391, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 204 Issue: 3-4
  • Publication Date: 2014
  • Doi Number: 10.1016/j.vetpar.2014.05.002
  • Journal Name: VETERINARY PARASITOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.388-391
  • Keywords: Babesia vogeli, Oxidative stress, Nitric oxide, 8-Hydroxy-2 '-deoxyguanosine, Total antioxidant capacity, OXIDATIVE STRESS, LIPID-PEROXIDATION, DISRUPTION, PLASMA, ASSAY
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Oxidative stress was defined as corruption of balance between oxidant-antioxidant states in favor of oxidants. In this study, it was aimed to determine oxidative stress in naturally infected dogs with Babesia vogeli. The 8-hydroxy-2'-deoxyguanosine (8-OHdG), nitric oxide (NO) and total antioxidant capacity (TAC) levels in the sera were analyzed by ELISA. 8-OHdG levels increased in B. vogeli infected dogs compared to control group (P < 0.05). Also, NO levels increased while TOC levels decreased in B. vogeli infected dogs but these variations were not found as statistically important (P > 0.05). (C) 2014 Elsevier B.V. All rights reserved.