Examination of the Relationship Between Average Plaque Volume and Clinical and Demographic Characteristics in Multiple Sclerosis Patients Using a Stereological Method
INTERNATIONAL JOURNAL OF NEUROSCIENCE, vol.121, no.7, pp.366-372, 2011 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 121 Issue: 7
- Publication Date: 2011
- Doi Number: 10.3109/00207454.2011.560313
- Journal Name: INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.366-372
- Keywords: Multiple sclerosis, prognosis, stereology, 3-DIMENSIONAL MRI, ATROPHY, BRAIN, DISABILITY, INFLAMMATION, PREDICTION
- Ondokuz Mayıs University Affiliated: Yes
Abstract
Aim: The objectives of this study were to investigate the lesion load on brain magnetic resonance images and the volume of different cerebral anatomical structures, in patients with a diagnosis of definite multiple sclerosis, using a stereological method. Methods: Fifty patients diagnosed with multiple sclerosis were included in the study. The volume fractions of the hemispheres, lateral ventricles, cerebellum, brain stem, and plaque volumes within the total brain volume were estimated. Results: The mean plaque volume was 0.83 +/-+/- 0.14 cm