Analysis of YKL-40 Acute-Phase Protein and Interleukin-6 Levels in Periodontal Disease
JOURNAL OF PERIODONTOLOGY, cilt.85, sa.9, ss.1240-1246, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 85 Sayı: 9
- Basım Tarihi: 2014
- Doi Numarası: 10.1902/jop.2014.130631
- Dergi Adı: JOURNAL OF PERIODONTOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1240-1246
- Anahtar Kelimeler: Acute-phase proteins, CHI3L1 protein, human, gingival crevicular fluid, interleukin-6, periodontal diseases, serum, YKL 40 protein, human, GINGIVAL CREVICULAR FLUID, C-REACTIVE PROTEIN, SERUM YKL-40, ENDOTHELIAL DYSFUNCTION, INFLAMMATORY BIOMARKER, RHEUMATOID-ARTHRITIS, MARKER, PLASMA, PARAMETERS, CYTOKINES
- Ondokuz Mayıs Üniversitesi Adresli: Evet
Özet
Background: YKL-40, a new acute-phase protein, is shown to be elevated in inflammatory diseases, such as rheumatoid arthritis, type 2 diabetes mellitus, and coronary artery diseases. However, there is no data indicating a relationship between YKL-40 and periodontal disease. Interleukin-6 (IL-6) is the major regulator of acute-phase protein synthesis and one of the most studied inflammatory markers in periodontal disease. The purpose of the present study is to evaluate YKL-40 and IL-6 levels in gingival crevicular fluid (GCF) and serum of patients with periodontal disease and healthy individuals.