Association of MEFV Gene Mutations With Rheumatoid Factor Levels in Patients With Rheumatoid Arthritis

İNANIR A., YİĞİT S., KARAKUŞ N., Tekin S., RÜSTEMOĞLU A.

JOURNAL OF INVESTIGATIVE MEDICINE, vol.61, no.3, pp.593-596, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 61 Issue: 3
  • Publication Date: 2013
  • Doi Number: 10.2310/jim.0b013e318280a96e
  • Journal Name: JOURNAL OF INVESTIGATIVE MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.593-596
  • Keywords: rheumatoid arthritis, MEFV gene, mutation, autoimmune disease, FAMILIAL MEDITERRANEAN FEVER, PROTRACTED ARTHRITIS, PYRIN, FREQUENCY, DISEASE, M694V, JEWS
  • Ondokuz Mayıs University Affiliated: No

Abstract

Purpose: Rheumatoid arthritis (RA) is a systemic autoimmune disease primarily affecting the joints. Arthritis disorders are associated with mutations of the Mediterranean fever (MEFV) gene. This gene has already been identified as being responsible for familial Mediterranean fever. The aim of this study was to explore the frequency and clinical significance of MEFV gene mutations in a cohort of Turkish patients with RA.