Association of MEFV Gene Mutations With Rheumatoid Factor Levels in Patients With Rheumatoid Arthritis

İNANIR A., YİĞİT S., KARAKUŞ N., Tekin S., RÜSTEMOĞLU A.

JOURNAL OF INVESTIGATIVE MEDICINE, cilt.61, sa.3, ss.593-596, 2013 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 61 Sayı: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.2310/jim.0b013e318280a96e
  • Dergi Adı: JOURNAL OF INVESTIGATIVE MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.593-596
  • Anahtar Kelimeler: rheumatoid arthritis, MEFV gene, mutation, autoimmune disease, FAMILIAL MEDITERRANEAN FEVER, PROTRACTED ARTHRITIS, PYRIN, FREQUENCY, DISEASE, M694V, JEWS
  • Ondokuz Mayıs Üniversitesi Adresli: Hayır

Özet

Purpose: Rheumatoid arthritis (RA) is a systemic autoimmune disease primarily affecting the joints. Arthritis disorders are associated with mutations of the Mediterranean fever (MEFV) gene. This gene has already been identified as being responsible for familial Mediterranean fever. The aim of this study was to explore the frequency and clinical significance of MEFV gene mutations in a cohort of Turkish patients with RA.