Epidemiological Characteristics of Inflammatory Bowel Diseases in the Last Decade: Multi Center Türkiye Data


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Akyüz F., Ağargün B. F., Atuğ Ö., Eşkazan T., Yüksel İ., Koçhan K., ...Daha Fazla

40th National Gastroenterology Week and 11th Congress of Gastrointestinal Surgery, Antalya, Türkiye, 21 - 26 Kasım 2023, cilt.34, sa.4, ss.28-30, (Tam Metin Bildiri)

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Cilt numarası: 34
  • Doi Numarası: 10.5152/tjg.2023.101123
  • Basıldığı Şehir: Antalya
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.28-30
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

 Background/Aims: This study aims to assess the past decade’s epi demiology of inflammatory bowel disease (IBD) patients in Turkey and identify year-to-year variations. Materials and Methods: A total of 3463 patients diagnosed between 2010 and 2022 were included. The patients’ demographic and phe notypic characteristics, smoking habits, and family histories were assessed. Differences between geographic regions and age groups were analyzed. Results: Among patients, 1523 (44%) had Crohn’s disease (CD), 1768 (51.1%) had ulcerative colitis (UC), and 23 (0.7%) had inde terminate colitis. Male proportions were higher in both CD and UC patients, with the most common age range for diagnosis being 21-30 years. Over time, newly diagnosed cases and rates per popu lation increased according to TÜİK data. Patients were divided into two groups based on diagnosis years (2010-2016 and 2016-2022), CD initially dominated, but UC prevalence grew in the last 6 years (P ≤ .001). Recently diagnosed CD patients showed higher inflamma tory involvement (78.0% vs. 63.4%; P ≤ .001), and the inflammatory phenotype rose post-2016 (75.2% vs. 60.4%; P ≤ .001). CD patients had more smokers (24.2% vs.10.9%; P ≤ 0.001) and family history of IBD (6.8% vs.4.5%; P = .004) than UC patients. Patients over 60 years old had a higher male gender ratio (64.4% vs. 55.9%; P ≤ .001) and UC frequency (62.2% vs. 52%; P ≤ .001) compared to those under 60 years old. The inflammatory phenotype in CD patients was lower in those under 60 years old compared to those over 60 years old (70.4% vs. 85.4%; P ≤ .001). The frequency of pancolitis in UC patients was lower in those over 60 years old (31.3% vs. 41.4%; P ≤ .001). Conclusion: In Turkey, IBD is more prevalent in males and is fre quently diagnosed between ages 20 to 30. In CD, inflammatory and ileocolonic involvement is most common, while in UC, pancolitis is observed. The earlier diagnosis peak and increased pancolitis in UC patients might relate to tertiary centers’ inclusion with transi tion clinics and focus on severe cases. Recently, newly diagnosed UC cases have notably surpassed CD cases