De Ritis ratio and biochemical parameters in COVID-19 patients

YAZAR H., Kayacan Y., Ozdin M.

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, vol.128, no.6, pp.1676-1680, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 128 Issue: 6
  • Publication Date: 2022
  • Doi Number: 10.1080/13813455.2020.1788604
  • Journal Name: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chemical Abstracts Core, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.1676-1680
  • Keywords: COVID-19, De Ritis ratio, AST, ALT, CK, CK-MB, LDH, ALANINE AMINOTRANSFERASE, SERUM ASPARTATE, AST/ALT
  • Ondokuz Mayıs University Affiliated: No

Abstract

Background The study aimed to examine some biochemical test parameters and De Ritis ratio in COVID-19 patients, considering age and gender. Method The study was performed on patients with real-time polymerase chain reaction and computed tomography lung diagnosis. The relationship between lactate dehydrogenase, creatine kinase (CK), creatine kinase-MB, alanine aminotransferase, aspartate aminotransferase and De Ritis ratio were analysed in the first blood samples of the patients. The difference between gender was also compared with the independent samplet-test. Alpha value was accepted Results The De Ritis was significantly higher in females (p = .040). The De Ritis ratio was associated with CK in both gender. There was no significant difference in the biochemical parameters according to gender. Conclusion The De Ritis ratio appears to be a parameter that can be used in COVID-19 patients. However, more detailed and comprehensive studies including the symptoms of patients are needed.