A case of neutrophilic dermatosis who develop palpable purpura during the use of montelukast

ÇETİN G. Y., Sayarlıoğlu H., Erhan C., KAHRAMAN H., ÇIRALIK H., Sayarlioglu M.

EUROPEAN JOURNAL OF RHEUMATOLOGY, vol.1, no.4, pp.170-171, 2014 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 1 Issue: 4
  • Publication Date: 2014
  • Doi Number: 10.5152/eurjrheumatol.2014.140032
  • Journal Name: EUROPEAN JOURNAL OF RHEUMATOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.170-171
  • Keywords: Neutrophilic dermatosis, leukotriene receptor antagonist, montelukast
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

In this case report, we present a female patient with neutrophilic dermatosis (ND) occurring as palpable purpura after using montelukast. Neutrophilic dermatoses (NDs) are characterized by skin lesions in which mature neutrophils are predominantly located in the epidermis and dermis in the absence of any infective pathology. Classification of the NDs is based upon the recognition of clinical and pathologic features, as well as the identification of associated diseases, like Sweet's syndrome, pyoderma gangrenosum, generalized pustular psoriasis, and Behcet's disease. Cutaneous findings in NDs are variable and can include vesiculopustules, plaques, nodules, or ulcerations. Drug-induced NDs are not uncommon, but ND with palpable purpura is uncommon. The current patient appeared with a rare presentation as palpable purpura without vasculitis regarding ND. It is important that this is the first case report.