Effects of subtelomeric copy number variations in miscarriages

TEKCAN A., Elbistan M., Tural Ş., Cetinkaya M. B.

GYNECOLOGICAL ENDOCRINOLOGY, cilt.31, sa.9, ss.708-714, 2015 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 9
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3109/09513590.2015.1032929
  • Dergi Adı: GYNECOLOGICAL ENDOCRINOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.708-714
  • Anahtar Kelimeler: Infertility, pregnancy, urogenital system, RECURRENT PREGNANCY LOSS, IN-SITU HYBRIDIZATION, 1ST-TRIMESTER MISCARRIAGES, SPONTANEOUS-ABORTION, PRENATAL-DIAGNOSIS, GENETIC-FACTORS, QF-PCR, MLPA, REARRANGEMENTS, COUPLES
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Purpose: This study was performed on miscarriage samples for chromosome analysis to detect copy number variations (CNVs) related to subtelomeric regions, and with these results we aimed to adapt multiplex ligation-dependent probe amplification (MLPA) method for prenatal diagnosis.