Effects of subtelomeric copy number variations in miscarriages

TEKCAN A., Elbistan M., Tural Ş., Cetinkaya M. B.

GYNECOLOGICAL ENDOCRINOLOGY, vol.31, no.9, pp.708-714, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 9
  • Publication Date: 2015
  • Doi Number: 10.3109/09513590.2015.1032929
  • Journal Name: GYNECOLOGICAL ENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.708-714
  • Keywords: Infertility, pregnancy, urogenital system, RECURRENT PREGNANCY LOSS, IN-SITU HYBRIDIZATION, 1ST-TRIMESTER MISCARRIAGES, SPONTANEOUS-ABORTION, PRENATAL-DIAGNOSIS, GENETIC-FACTORS, QF-PCR, MLPA, REARRANGEMENTS, COUPLES
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Purpose: This study was performed on miscarriage samples for chromosome analysis to detect copy number variations (CNVs) related to subtelomeric regions, and with these results we aimed to adapt multiplex ligation-dependent probe amplification (MLPA) method for prenatal diagnosis.