Effects of subtelomeric copy number variations in miscarriages
GYNECOLOGICAL ENDOCRINOLOGY, vol.31, no.9, pp.708-714, 2015 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 31 Issue: 9
- Publication Date: 2015
- Doi Number: 10.3109/09513590.2015.1032929
- Journal Name: GYNECOLOGICAL ENDOCRINOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.708-714
- Keywords: Infertility, pregnancy, urogenital system, RECURRENT PREGNANCY LOSS, IN-SITU HYBRIDIZATION, 1ST-TRIMESTER MISCARRIAGES, SPONTANEOUS-ABORTION, PRENATAL-DIAGNOSIS, GENETIC-FACTORS, QF-PCR, MLPA, REARRANGEMENTS, COUPLES
- Ondokuz Mayıs University Affiliated: Yes
Abstract
Purpose: This study was performed on miscarriage samples for chromosome analysis to detect copy number variations (CNVs) related to subtelomeric regions, and with these results we aimed to adapt multiplex ligation-dependent probe amplification (MLPA) method for prenatal diagnosis.