The effect of trimetazidine on renal oxidative stress in partial and complete ureteral obstructions in a rat model

Ayyildiz S. N., Ayyildiz A., BENLİ E., CIRRIK S., Germiyanoğlu R. C., NOYAN T., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.47, no.3, pp.1012-1018, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.3906/sag-1512-85
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1012-1018
  • Keywords: Ureteral obstruction, renal oxidative stress, trimetazidine, renal function, INJURY, DAMAGE, POLYMORPHISMS
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Background/aim: Renal oxidative stress occurs in ureteral obstructions. The purpose of this study was to investigate the effect of the antioxidant and antiischemic agent trimetazidine (TMZ) on oxidative stress following ureteral obstruction.