JOURNAL OF KING SAUD UNIVERSITY SCIENCE, vol.32, no.4, pp.2500-2504, 2020 (SCI-Expanded)
Article / Article
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, zbMATH, Directory of Open Access Journals
Multicomponent cycloaddition strategy, Ferrocene grafted spiroheterocyles, Indenoquinoxaline, Ionic liquids, 1,3-DIPOLAR CYCLOADDITION REACTIONS, ANTIMALARIAL ACTIVITY, IN-VITRO, MULTICOMPONENT
Ondokuz Mayıs University Affiliated:
Spiropyrrolidine engrafted ferrocene heterocycles were synthesized in excellent yields in a sustainable fashion employing an ionic liquid, 1-butyl-3-methylimidazoliumbromide accelerated one-pot multicomponent cycloaddition strategy. The in situ 1,3-dipole component derived from indenoquinoxalinone and L-phenylalanine that reacts with various substituted ferrocenyl chalcone in [bmim]Br affording spirocycloadduct. (C) 2020 The Author(s). Published by Elsevier B.V. on behalf of King Saud University.