Phytochemical constituents and antioxidant effect of solanum rostratum species from algeria
Asian Journal of Pharmaceutical and Clinical Research, cilt.11, sa.6, ss.219-223, 2018 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 11 Sayı: 6
- Basım Tarihi: 2018
- Doi Numarası: 10.22159/ajpcr.2018.v11i6.24951
- Dergi Adı: Asian Journal of Pharmaceutical and Clinical Research
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.219-223
- Anahtar Kelimeler: Antioxidant, Flavonoid glycosides, Monoterpene glycoside, Solanum rostratum
- Ondokuz Mayıs Üniversitesi Adresli: Hayır
Özet
Objective: The aim of this study was to isolate the constituents and evaluate the antioxidant activity of Solanum rostratum Dunal (Solanaceae) from Algeria. Methods: In this study, phytochemical analyses of the chloroform, ethyl acetate, and n-butanol extracts obtained from the aerial parts of S. rostratum were performed by column chromatography, thin-layer chromatography, and high-performance liquid chromatography techniques. The antioxidant activity was performed by 2,2-diphenyl-1-picrylhydrazyl scavenging assay method. Results: The identification and structure elucidation of the isolated compounds were compared with their nuclear magnetic resonance spectra and the literature led to identify one monoterpene glycoside (linalyl-β-glucopyranoside) (1) and three flavonoid glycosides: Apigenin-7-O-glucoside (2), astragalin (3) and (isorhamnetin-3-O-glucoside (4). Conclusion: This is the first report on the isolation and structure elucidation of compound (1) (linalyl-β-glucopyranoside) and compound (2) (apigenin-7-O-glucoside) from this species. In addition, antioxidant effect of the chloroform extract from S. rostratum was evaluated. The chloroform extract exhibited the remarkable radical scavenging ability (IC50 =0066±0.001 mg/mL).