Rapid Verification of Unusual Tracer Uptake Patterns by Means of SPECT/CT A Case of Unexpected (111)Indium Pentetreotide Accumulation in a Splenic Variant

Canbaz Tosun F., Basoglu T., Ersoy D., Dabak N.

CLINICAL NUCLEAR MEDICINE, vol.35, no.11, pp.904-906, 2010 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Editorial Material
  • Volume: 35 Issue: 11
  • Publication Date: 2010
  • Doi Number: 10.1097/rlu.0b013e3181f4a025
  • Journal Name: CLINICAL NUCLEAR MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.904-906
  • Keywords: atypical, spleen, SPECT/CT, Indium 111-pentetreotide
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

A 45-year-old woman with gluteal mass and a histopathological diagnosis of malign small round cell sarcoma was investigated for metastatic spread. The patient was referred to nuclear medicine for further evaluation by means of somatostatin analogues. (111)Indium-pentetreotide whole body imaging revealed an intense and inverted arrow-shaped uptake in the left upper quadrant resembling cardiac activity. Although the location and posterior appearance of the tracer uptake was indicating somehow splenic activity, a SPECT/CT scan was performed for anatomic verification. The reconstructed SPECT/CT fusion images depicted clearly that the totality of the atypical activity originated from the spleen, which was defined as an anatomic variant. In this case, SPECT/CT easily clarified the unusual appearance of the spleen, suggesting a pathologic finding on conventional whole body imaging.