Shared Biological Pathways and Processes in Patients with Intellectual Disability: A Multicenter Study

GÜNAY Ç., AYKOL D., ÖZSOY Ö., Sonmezler E., Hanci Y. S., KARA B., ...More

NEUROPEDIATRICS, vol.54, no.4, pp.225-238, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 4
  • Publication Date: 2022
  • Doi Number: 10.1055/a-2034-8528
  • Journal Name: NEUROPEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, EMBASE, MEDLINE
  • Page Numbers: pp.225-238
  • Keywords: neurodevelopmental disorder, intellectual disability, pathway analysis, enrichment analysis, KEGG, ontology, ASSOCIATION, METABOLISM, CHANNELS, INSIGHTS, GENETICS, GENES, TOOL
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Background Although the underlying genetic causes of intellectual disability (ID) continue to be rapidly identified, the biological pathways and processes that could be targets for a potential molecular therapy are not yet known. This study aimed to identify ID-related shared pathways and processes utilizing enrichment analyses.