Synthesis and Structural and Biochemical Activity Studies of Dioxime Ligand and its Mononuclear Cu(II), Ni(II), and Co(II) Complexes


KARABÖCEK N., Armutcu M., KARABÖCEK S., TANAK H., Isik S., Baskan O.

SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY, vol.41, no.10, pp.1249-1256, 2011 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 10
  • Publication Date: 2011
  • Doi Number: 10.1080/15533174.2011.591878
  • Journal Name: SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
  • Page Numbers: pp.1249-1256
  • Keywords: antimicrobial activity, dione dioxime, metal complexes, SCHIFF-BASE LIGANDS, COPPER(II) COMPLEXES, METAL-COMPLEXES, 1ST EVIDENCE, BOND, ZN(II)
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

A new tetradentate ligand incorporating dioxime moities has been synthesized. Its copper(II), nickel(II), and cobalt(II) complexes have been prepared and characterized by spectral methods. Elemental analyses and spectroscopic data of the metal complexes are consistent with the formation of the mononuclear copper(II), nickel(II) and cobalt(II) complexes. The crystal structure of the (2E, 2'E)-butane-2,3-dione 2,2'-{O-2,O-2'-[1,2-phenylenebis(methylene)]oxime compound (3) was determined by single-crystal x-ray diffraction technique. The free ligand and copper(II), nickel(II), and cobalt(II) complexes (5-7) were tested against the morphology of series bacteria. The Cu(II), Ni(II), and Co(II) complexes exhibit higher activity than dioxime ligand under identical experimental conditions.