Significance of cagA status and vacA subtypes of Helicobacter pylori in determining gastric histopathology: Virulence markers of H-pylori and histopathology

KAKLIKKAYA, NEŞE; Cubukcu, Kivanc; AYDIN, FARUK; Bakir, Tulay; Erkul, Suat; Tosun, Ilknur; Topbas, Murat; Yazici, Yelda; Buruk, Celal; Erturk, Murat

doi:10.1111/j.1440-1746.2006.04199.x

Significance of cagA status and vacA subtypes of Helicobacter pylori in determining gastric histopathology: Virulence markers of H-pylori and histopathology

KAKLIKKAYA N., Cubukcu K., AYDIN F., Bakir T., Erkul S., Tosun I., ...Daha Fazla

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, cilt.21, sa.6, ss.1042-1047, 2006 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 21 Sayı: 6
Basım Tarihi: 2006
Doi Numarası: 10.1111/j.1440-1746.2006.04199.x
Dergi Adı: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1042-1047
Anahtar Kelimeler: cagA status, Helicobacter pylori, histopathology, vacA subtypes, VACUOLATING CYTOTOXIN, SYDNEY SYSTEM, PEPTIC-ULCER, GENE, ASSOCIATION, EXPRESSION, GENOTYPES, STRAINS, CLASSIFICATION, DIVERSITY
Ondokuz Mayıs Üniversitesi Adresli: Hayır

Özet

Background: It has been suggested that Helicobacter pylori strains containing the cytotoxin-associated gene A (cagA), and s1m1 genotype of vacuolating cytotoxin gene A (vacA) may have been associated with peptic ulcer disease. The aim of the present study was to analyze such an association of cagA presence and vacA subtypes of H. pylori with histopathological findings in patients with gastritis.