Synthesis, characterization, crystal structure and biological activities of supramolecular compounds of Mn(II) and Zn(II) with dipicolinic acid and 8-hydroxyquinoline

ÇOLAK A. T., ÇOLAK F., YEŞİLEL O. Z., Buyukgungor O.

JOURNAL OF COORDINATION CHEMISTRY, vol.62, no.10, pp.1650-1660, 2009 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 62 Issue: 10
  • Publication Date: 2009
  • Doi Number: 10.1080/00958970802676656
  • Journal Name: JOURNAL OF COORDINATION CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1650-1660
  • Keywords: Dipicolinic acid, 8-Hydroxyquinoline, Antimicrobial activity, PROTON-TRANSFER COMPOUND, 2,6-PYRIDINEDICARBOXYLIC ACID, ZINC(II) COMPLEXES, HYDROGEN-BONDS, MONOHYDRATE, PYRIDINE
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Two compounds, (8-H2Q)2[Mn(dipic)2] 6H2O (1) and (8-H2Q)2[Zn(dipic)2] 6H2O (2) (8-HQ = 8-hydroxyquinoline (oxine), H2dipic = dipicolinic acid), have been prepared and characterized by elemental, spectroscopic (IR and UV-Vis), and thermal analyses, magnetic measurements and single crystal X-ray diffraction techniques. Compounds 1 and 2 consist of two 8-hydroxyquinolinium cations, one bis(dipicolinato)M(II) anion (M = Mn(II) and Zn(II)) and six uncoordinated water molecules. Both 1 and 2 crystallize in the monoclinic space group C2/c. In the complex anion, each dipic ligand is tridentate through N of pyridine and oxygens of the carboxylate groups. Crystal packing of 1 and 2 is a composite of intermolecular hydrogen bonding interactions. The in vitro antibacterial and antifungal activities of 1 and 2 were evaluated by the agar well diffusion method by MIC (Minimal Inhibition Concentration), looking for compounds which display high-inhibitory effect against gram positive bacteria and fungi. No growth inhibition was observed against tested gram negative bacteria.