Does subthalamic nucleus deep brain stimulation affect the static balance at different frequencies? ¿La estimulación cerebral profunda del núcleo subtalámico afecta el equilibrio estático en diferentes frecuencias?

Oz F., Yucekeya B., Huzmeli I., Yilmaz A.

Neurocirugia, vol.34, no.2, pp.60-66, 2023 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 2
  • Publication Date: 2023
  • Doi Number: 10.1016/j.neucir.2022.01.001
  • Journal Name: Neurocirugia
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, DIALNET
  • Page Numbers: pp.60-66
  • Keywords: Parkinson's disease, Static balance, Stimulation frequency, Subthalamic nucleus deep brain stimulation
  • Ondokuz Mayıs University Affiliated: No


Purpose: To investigate the effects of bilateral subthalamic nucleus deep brain stimulation (STN-DBS) with different stimulation frequencies on static balance. Materials and methods: Twenty patients (15 males and 5 females), aged between 43 and 81 (mean: 60.05 ± 7.4) years, who had been diagnosed with idiopathic Parkinson's disease (PD) and undergone STN-DBS surgery were included in the study. Static balance was assessed with TecnoBody Rehabilitation System at four different frequencies: 230, 130, 90 and 60 Hz and off-stimulation. Static balance tests were ‘stabilometric test, stabilometric compared bipedal closed/opened eye, stabilometric compared mono pedal (right/left foot)’. These tests reported the centre of pressure data ‘ellipse area, perimeter, front/back and mediolateral standard deviations’. Results: There were no statically differences between the static balance test results at any frequency (p > 0.05), but results were found better at 90 Hz. Stabilometric compared bipedal opened eye forward–backward standard deviation result was significant between off-stimulation and 130 Hz (p = 0.04). Different frequency stimulation affected the static balance categories percentage with no statistical significance between off-stimulation and others (all p > 0.05). Conclusion: This study showed that STN-DBS did not affect the static balance negatively. Low-frequency (LF) stimulation improved the static equilibrium. Posturography systems will give more precise and quantitative results in similar studies with wide frequency ranges.