An evaluation of false-positive rifampicin resistance on the Xpert MTB/RIF

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Tanrıverdi Çaycı Y., BİLGİN K., Coban A. Y., Birinci A., Durupinar B.

MEMORIAS DO INSTITUTO OSWALDO CRUZ, vol.112, no.11, pp.756-759, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 112 Issue: 11
  • Publication Date: 2017
  • Doi Number: 10.1590/0074-02760170051
  • Journal Name: MEMORIAS DO INSTITUTO OSWALDO CRUZ
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.756-759
  • Keywords: Mycobacterium tuberculosis, rifampicin resistance, Xpert MTB/RIF assay, MYCOBACTERIUM-TUBERCULOSIS INFECTIONS, DIAGNOSIS, REINFECTION, MUTATIONS, PULMONARY, ASSAY
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

BACKGROUND Mycobacterium tuberculosis (MTB) is one of the most significant causes of mortality and morbidity. Early diagnose is important especially in multiple drug resistant tuberculosis to avoid transmission. Traditional techniques requires at least one to three weeks for diagnosis of tuberculosis. Diagnostic delays with multiple drug resistant tuberculosis are associated with worse clinical outcomes and increased transmission The Xpert MTB/RIF assay is one of the new diagnostic device for the diagnosis of tuberculosis and rapid detection of rifampicin resistance.