Aim: The aim of this study was to assess the apical sealing ability of Resilon™ obturation material. Methods and Materials: Forty-two single rooted extracted human teeth were selected and randomly divided into three groups. They were obturated using lateral condensation with gutta-percha and AH 26/AH plus and Resilon™; also, 12 root canals were used as control groups. The apical leakage was measured using the dye penetration methodology. Results: The teeth filled with gutta-percha and AH 26 displayed the most apical leakage. The least apical leakage was shown with Resilon™ Discussion: The differences in leakage among the groups, gutta-percha with AH 26 (2.4 mm, SD:1.87), gutta-percha with AH plus (2.1 mm, SD: 1.69), and Resilon™ (1.7 mm, SD:1.32), were statistically significant (p< 0.001). Conclusion: Based on the data of this study, all groups produced a satisfactory seal. However, Resilon™ and Epiphany™ sealer showed the least apical leakage.