Interaction Between Periodontal Disease and Systemic Secondary Amyloidosis: From Inflammation to Amyloidosis

CENGİZ M. İ., Yayla N., Cengiz K., Bagci H., Taskin E.

JOURNAL OF PERIODONTOLOGY, vol.82, no.4, pp.566-574, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 82 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.1902/jop.2010.100439
  • Journal Name: JOURNAL OF PERIODONTOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.566-574
  • Keywords: Acute-phase proteins, genetics, periodontal diseases, FAMILIAL-MEDITERRANEAN-FEVER, PHENOTYPE-GENOTYPE CORRELATION, AA AMYLOIDOSIS, HEMODIALYSIS-PATIENTS, MARKERS, PROGNOSIS, DIALYSIS, ETIOLOGY, THERAPY, TURKEY
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Background: It has become increasingly clear in recent years that periodontal disease can cause a dramatic increase in the levels of markers of systemic inflammation, and that periodontal treatment can result in reduction in the levels of these markers. We have previously shown that the prevalence of moderate to severe periodontitis was significantly higher in patients with familial Mediterranean fever (FMF) with amyloidosis than in patients with FMF without amyloidosis. Thus, the aim of this study is to investigate if chronic periodontitis is associated with secondary amyloidosis in the Black Sea region of Turkey.