Vascular endothelial growth factor expression levels of gingiva in gingivitis and periodontitis patients with/without diabetes mellitus

Keles G. C., Özkan Çetinkaya B., Eroglu C., Simsek S. B., Kahraman H.

INFLAMMATION RESEARCH, vol.59, no.7, pp.543-549, 2010 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 7
  • Publication Date: 2010
  • Doi Number: 10.1007/s00011-010-0158-8
  • Journal Name: INFLAMMATION RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.543-549
  • Keywords: Diabetes mellitus, mRNA expression, Periodontal disease, Vascular endothelial growth factor, CREVICULAR FLUID, MESSENGER-RNA, PERMEABILITY FACTOR, VEGF LEVELS, DISEASE, HEALTHY, ANGIOGENESIS, COMPLICATIONS, RETINOPATHY, TISSUES
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

The aim of this study was to determine vascular endothelial growth factor (VEGF) mRNA expression levels in gingival tissues of gingivitis and periodontitis patients with diabetes mellitus and those without. The hypothesis tested is that expression of VEGF, considered the effective cytokine in the relationship between diabetes and periodontal disease, is differentially affected in gingivitis and periodontitis patients with or without diabetes mellitus compared to healthy controls.