Effects of acetyl salicylate and ibuprofen on fluoroquinolone MICs on Salmonella enterica serovar typhimurium in vitro

Coban A., Birinci A., Ekinci B., Durupinar B.

JOURNAL OF CHEMOTHERAPY, vol.16, no.2, pp.128-133, 2004 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 2
  • Publication Date: 2004
  • Doi Number: 10.1179/joc.2004.16.2.128
  • Journal Name: JOURNAL OF CHEMOTHERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.128-133
  • Keywords: acetylsalicylate, ibuprofen, Salmonella enterica serovar typhimurium, ESCHERICHIA-COLI, ANTIBIOTIC-RESISTANCE, KLEBSIELLA-PNEUMONIAE, STAPHYLOCOCCUS-AUREUS, MULTIDRUG-RESISTANCE, MAR LOCUS, CHLORAMPHENICOL, SUSCEPTIBILITY, ACCUMULATION, POTENTIATION
  • Ondokuz Mayıs University Affiliated: No

Abstract

In this study, the effects of acetylsalicylate and ibuprofen at 2, 4 and 8 mM concentration were investigated on ofloxacin, ciprofloxacin, levofloxacin and pefloxacin minimum inhibitory concentrations (MICs) for 14 Salmonella enterica serovar typhimurium clinical isolates, one standard strain (SZH KUEN 557), SH7616 (acr mutant), SH5014 (parent strain of acr mutant) and PP120 (soxRS mutant) strains.