Increased Expression of Interleukin-18 mRNA is Associated with Carotid Artery Stenosis

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Arapi B., Bayoglu B., CENGİZ M., DİRİCAN A., Deser S. B., Junusbekov Y., ...More

BALKAN MEDICAL JOURNAL, vol.35, no.3, pp.250-255, 2018 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.4274/balkanmedj.2017.0323
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.250-255
  • Keywords: Carotid artery, gene expression, interleukin-18, interleukin-18-binding protein, stenosis, ACUTE MYOCARDIAL-INFARCTION, IL-18 PRODUCTION, ADRENAL-CORTEX, DISEASE, ATHEROSCLEROSIS, POLYMORPHISMS, CYTOKINE, PROMOTER, RECEPTOR, MARKERS
  • Ondokuz Mayıs University Affiliated: Yes


Background: Carotid artery stenosis is the atherosclerotic narrowing of the proximal internal carotid artery and one of the primary causes of stroke. Elevated expression of the pleiotropic proinflammatory cytokine interleukin-18 has been demonstrated in human atherosclerotic plaques.