Attenuation of bleomycin induced lung fibrosis by erdosteine and inhibition of the inducible nitric oxide synthase

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Guzel A., Kayhan S., Tutuncu Ş., Guzel A., Duran L., Alacam H., ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.116, no.3, pp.196-202, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 116 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.4149/bll_2015_039
  • Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.196-202
  • Keywords: bleomycine, pulmonary fibrosis, erdosteine, S-methylisothiourea, rats, IDIOPATHIC PULMONARY-FIBROSIS, S-METHYLISOTHIOUREA, METABOLITE-I, PEROXYNITRITE, INFLAMMATION, CELLS, RATS, PATHOGENESIS, GENERATION, INJURY
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Background and objectives: Despite advances in treatment modalities, the discovery of optimal medical therapies still remains a necessity in the management of pulmonary fibrosis.