Inflammatory Bowel Disease (IBD) is an idiopathic and chronic gastrointestinal failure of cats, dogs and some farm animals such as horses. Since the long and difficult classical therapy of the disease has various side effects such as malignancy and lymphoma, new therapeutic methods are needed. However, a safe and standardized treatment protocol has not been developed, yet. Therefore, IBD treatment is still a big dilemma for both veterinary and human medicine. In this review, IBD and new possible therapeutic alternatives were evaluated for dogs.