Nutritional Foundations of Holistic Health: From Supplements to Feed Strategies, In: Şahin T,Ameer K,Abid M and Tahir S (eds), Editör, A Publication of Unique Scientific Publishers, Faisalabad, ss.106-111, 2025
Ruminant meat contains high levels of saturated fats and low levels of polyunsaturated fats and has therefore been targeted for improvement of its fatty acid profile to be consistent with human dietary recommendations. Sources of dietary fat can affect gene expression of enzymes involved in the fatty acid (FA) profile of ruminant meat. The biochemical regulation of the meat's FA profile consists of complicated mechanisms which incorporate both genetic elements and dietary nutrients. The research focus of nutrigenomics is to modulate and monitor this metabolic process. There has been great interest in understanding how transcription factors control lipid and FA metabolism in this context. The available evidence suggests that gene expression is a key metabolic determinant driving ruminant meat FA profile and lipid accumulation. Moreover, the expression of these lipid-related genes is dependent on the composition and nutrient content of the diet. This chapter describes how nutrition influences the gene expressions associated with lipid metabolism and how dietary manipulations may change the fatty acid profile of ruminant meat