RHEUMATOLOGY INTERNATIONAL, vol.27, no.1, pp.87-89, 2006 (SCI-Expanded)
Hepatocellular carcinoma (HCC) may be present in one of the several ways. The classical presentation is with right upper quadrant abdominal pain, abdominal swelling and weight loss. HCC may also be associated with several paraneoplastic manifestations. The mechanisms of these manifestations are not well known. The association of digital ischemia and malignancy was reported as early as 1884 and 1891. We report a case of HCC associated with Raynaund's phenomenon.