Symmetric polyarthritis as an initial symptom in granulomatosis with polyangiitis: A report of six cases and review of the literature

Kisacik B., Onder M. E., Sayarlioglu M., Onat A. M.

EUROPEAN JOURNAL OF RHEUMATOLOGY, vol.5, no.3, pp.191-193, 2018 (ESCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 5 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.5152/eurjrheum.2018.17050
  • Journal Name: EUROPEAN JOURNAL OF RHEUMATOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.191-193
  • Keywords: Granulomatosis with polyangiitis, arthritis, WEGENERS-GRANULOMATOSIS, RHEUMATOID-ARTHRITIS
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Granulomatosis with polyangiitis (GPA) is a primary systemic vasculitis characterized by granulomatous inflammation. Arthritis in GPA is most commonly associated with large joints, particularly the knees and ankles; however, symmetrical polyarthritis of small joints has been rarely reported in literature. Here, we describe retrospective analysis of six patients with GPA showing initial symptom of symmetrical polyarthritis who were followed-up by three different rheumatology departments. Male sex, anti-cyclic citrulinated peptide negativity, and early arthritis period are important clues for GPA.