Stress plays a role in the pathogenesis of Feline Idiopathic Cystitis (FIC) and behavioural management to reduce stress is indispensable in the FIC patients. The effectiveness of using a new digital health application (DHA) in reducing the recurrence of symptoms in FIC was investigated within this study.

Thirty owned cats of different age, breed and gender diagnosed with FIC who were brought to Animal Hospital. DHA (KEDIMED®) that can be downloaded to mobile phones has been developed. Thirty cats were randomly divided into Placebo (P), Prazosin (PZ) and Prazosin+ KEDIMED (PZ+KDM) with 10 cats in each group. Multimodal Environmental Modification (MEMO) was administered to all groups. Patients in the P group received oral placebo gel capsules bid for 30 days, PZ group received oral prazosin 0.25 mg/cat orally bid for 30 days. PZ+KDM group, 0.25 mg/cat prazosin was administered orally bid for 30 days with KEDIMED® monitoring.

A significant decrease (<0.05) was found between the groups in the group, time, and time*group comparisons of Feline Emotional and Quality of Life Scaling Data on the day zero before treatment and 30th day after treatment. A statistical difference (<0.05) was also found between P and PZ+KDM groups when comparing inter group data.

In conclusion, MEMO should be added to the primary treatment in FIC, that being in con- stant contact with the patient’s relatives to better manage this long-term process reducing mortality and recurrence, and KEDIMED® DHA had an important effect on establishing this bond with the patient’s relatives.