Voltammetric Study of the Complexation of Propafenone Hydrochloride (Rythmol SR) with Co<SUP>2+</SUP>, Ni<SUP>2+</SUP>, Zn<SUP>2+</SUP>, and Mn<SUP>2+</SUP> Ions

Billy T. A., Biçer E.

RUSSIAN JOURNAL OF ELECTROCHEMISTRY, vol.59, no.10, pp.797-808, 2023 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 10
  • Publication Date: 2023
  • Doi Number: 10.1134/s1023193523100038
  • Journal Name: RUSSIAN JOURNAL OF ELECTROCHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aqualine, Chemical Abstracts Core, Chimica, Compendex, Environment Index, INSPEC
  • Page Numbers: pp.797-808
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Square-wave (SW) voltammetric investigation of the binding processes of propafenone hydrochlo-ride (PFOH) with Co2+, Ni2+, Zn2+, and Mn2+ ions was carried out at pH of 7.4. For the formed complexes, both average stoichiometries and stability constants were found by means of modified De Ford-Humemethod. According to SW voltammetric data, the metal : ligand ratio of 1 : 2 for Mn2+ was obtained. More-over, PFOH formed complexes in average metal : ligand ratio of 1 : 2 for Ni2+ and Zn2+; however, this averageratio was 1 : 6 for the Co2+ complex in the solution phase. The order of their stability constants was observed to obey Co(PFOH)(6) >> Ni(PFOH)(2) > Zn(PFOH)(2) > Mn(PFOH)(2). Also, the ligand numbers and formation constants of the successively formed Co(PFOH)(j), Ni(PFOH)(j), and Zn(PFOH)(j) complexes in solution phase were calculated.