Is resveratrol a potential substitute for leuprolide acetate in experimental endometriosis?

Tekin, Yesim; GÜVEN, SÜLEYMAN; Kirbas, AYNUR; Kalkan, YILDIRAY; Tumkaya, Levent; GUVEN, Emine

doi:10.1016/j.ejogrb.2014.10.041

Is resveratrol a potential substitute for leuprolide acetate in experimental endometriosis?

Tekin Y. B., GÜVEN S., Kirbas A., Kalkan Y., Tumkaya L., GUVEN E. S. G.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, cilt.184, ss.1-6, 2015 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 184
Basım Tarihi: 2015
Doi Numarası: 10.1016/j.ejogrb.2014.10.041
Dergi Adı: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1-6
Anahtar Kelimeler: Endometriosis, Rat model, Resveratrol, Leuprolide acetate, Treatment, RAT MODEL, REGRESSION, TISSUE, INVASIVENESS, ANGIOGENESIS, INFLAMMATION, INHIBITOR, EXPLANTS, IMMUNE
Ondokuz Mayıs Üniversitesi Adresli: Hayır

Özet

Objective: Resveratrol, a phytoalexin polyphenol, has anti-angiogenic, antioxidant, anti-inflammatory properties. We aimed to compare the anti-inflammatory and anti-angiogenic effects of resveratrol and leuprolide acetate (LA) in an experimental endometriosis model.