The Preventive Effect of Curcumin on the Experimental Rat Epidural Fibrosis Model

Demirel C., Turkoz D., Yazicioglu I. M., Çokluk C.

WORLD NEUROSURGERY, vol.145, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 145
  • Publication Date: 2021
  • Doi Number: 10.1016/j.wneu.2020.09.140
  • Journal Name: WORLD NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Index Islamicus, MEDLINE, Veterinary Science Database
  • Keywords: Curcumin, Epidural fibrosis, Granulation, Inflammation, Laminectomy, LUMBAR DISC SURGERY, GROWTH-FACTOR, LAMINECTOMY, EXPRESSION, DECORIN, SCAR, 5-FLUOROURACIL, COMBINATION, INHIBITION, REPAIR
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

OBJECTIVE: The aim of the study was to evaluate the effect of systemically administrated curcumin on the prevention of peridural fibrotic tissue and adhesion formation in a rat laminectomy model.