Effects of gadolinium-based MRI contrast agents on liver tissue

Mercantepe, Tolga; Tumkaya, Levent; Celiker, FATMA; Suzan, Zehra; Cinar, Seda; Akyildiz, KERİMALİ; Mercantepe, Filiz; Yilmaz, Adnan

doi:10.1002/jmri.26031

Effects of gadolinium-based MRI contrast agents on liver tissue

Mercantepe T., Tumkaya L., Celiker F., Suzan Z. T., Cinar S., Akyildiz K., ...More

JOURNAL OF MAGNETIC RESONANCE IMAGING, vol.48, no.5, pp.1367-1374, 2018 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 48 Issue: 5
Publication Date: 2018
Doi Number: 10.1002/jmri.26031
Journal Name: JOURNAL OF MAGNETIC RESONANCE IMAGING
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1367-1374
Keywords: gadodiamide, gadoteric acid, apoptosis, oxidative stress, liver, rat, OXIDATIVE STRESS, TOXICITY, CHLORIDE, RETENTION
Ondokuz Mayıs University Affiliated: No

Abstract

BackgroundPurposeMRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models.