Comparative efficacy of pegylated interferons alpha-2a and 2b in the treatment of HBeAg-negative chronic Hepatitis B infection

Karabay O., Tuna N., Esen Ş.

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, vol.24, no.11, pp.1296-1301, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 11
  • Publication Date: 2012
  • Doi Number: 10.1097/meg.0b013e328356eac2
  • Journal Name: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1296-1301
  • Keywords: chronic hepatitis B, pegylated interferon, treatment, E-ANTIGEN, PEGINTERFERON ALPHA-2A, HBSAG LOSS, VIRUS, THERAPY, EPIDEMIOLOGY, COMBINATION, LAMIVUDINE, GENOTYPES, TURKEY
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Introduction Interferons, pegylated interferons (PegIFN), and oral antivirals are used in the treatment of chronic hepatitis B (CHB) virus infection. The number of studies comparing the efficacy of PegIFNs in the treatment of HBe antigen-negative CHB is rather limited. In this trial, the efficacy of two PegIFN products used in the treatment of CHB is compared.