Acquired von Willebrand syndrome in a patient with Ewing sarcoma

Elli M., Pinarli F., Dagdemir A., Dabak N., Fisgin T., Selcuk M., ...More

PEDIATRIC HEMATOLOGY AND ONCOLOGY, vol.23, no.2, pp.111-114, 2006 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 2
  • Publication Date: 2006
  • Doi Number: 10.1080/08880010500457749
  • Journal Name: PEDIATRIC HEMATOLOGY AND ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.111-114
  • Keywords: acquired von Willebrand syndrome, Ewing sarcoma
  • Ondokuz Mayıs University Affiliated: No

Abstract

Acquired von Willebrand syndronze is a rare bleeding disorder with clinical and laboratory features closely resembling to hereditary von Willebrand disease. The syndrome may accompany various conditions, including malignant disorders, most often with Wilms tumor and adrenal cell carcinoma. In this report, the authors present a patient with AvWS in association with Ewing sarcoma for the first time in the literature. The abnormal bleeding tendency was successfully treated with fresh frozen plasma and did not recur after the first two courses of chemotherapy with clinical improvement.