Influence of ESR1 Variants on Clinical Characteristics and Fibromyalgia Syndrome in Turkish Women

Arslan H. S., NURSAL A. F., Inanir A., KARAKUŞ N., YİĞİT S.

ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, vol.21, no.7, pp.1326-1332, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 7
  • Publication Date: 2021
  • Doi Number: 10.2174/1871530320666200910110915
  • Journal Name: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
  • Page Numbers: pp.1326-1332
  • Keywords: Fibromiyalgia syndrome, estrogen receptor-alpha, Pvull, XbaI, variant, women, PREMATURE OVARIAN FAILURE, GENETIC POLYMORPHISMS, ESTROGEN, RISK, PVUII, INVOLVEMENT
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Background: Fibromyalgia syndrome (FMS) is characterized by widespread musculoskeletal pain. It is more common in women than in men, and sex hormones may play a role in this predominance. Therefore, this research investigated the clinical findings among Turkish females and whether Estrogen-alpha (ESR1) gene variants are associated with FMS.