The frequency of CCR5delta32 polymorphism in the central Black Sea coastal region in a healthy population
TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.37, sa.1, ss.17-19, 2007 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 37 Sayı: 1
- Basım Tarihi: 2007
- Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.17-19
- Anahtar Kelimeler: chemokine receptor, delta32, Turkish people, HIV-1 INFECTION, GENE, INDIVIDUALS, RESISTANCE, ALLELE
- Ondokuz Mayıs Üniversitesi Adresli: Evet
Özet
Aim: Delta32 polymorphism in the chemokine receptor 5 (CCR5) gene affects human immune deficiency virus type 1 (HIV-1) entry, transmission, and outcome. The aim of this study was to determine the allelic frequencies of genetic variant CCR5delta32, which influence susceptibility to HIV-1 infection, in a northern Turkish population.