The frequency of CCR5delta32 polymorphism in the central Black Sea coastal region in a healthy population

Guenes S. O., Kara N., Bagci H.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.37, no.1, pp.17-19, 2007 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 1
  • Publication Date: 2007
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.17-19
  • Keywords: chemokine receptor, delta32, Turkish people, HIV-1 INFECTION, GENE, INDIVIDUALS, RESISTANCE, ALLELE
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Aim: Delta32 polymorphism in the chemokine receptor 5 (CCR5) gene affects human immune deficiency virus type 1 (HIV-1) entry, transmission, and outcome. The aim of this study was to determine the allelic frequencies of genetic variant CCR5delta32, which influence susceptibility to HIV-1 infection, in a northern Turkish population.