Mitochondrial Dysfunction and mTOR in Autism Spectrum Disorders

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Selamet E., USTA M. B.

Psikiyatride Güncel Yaklaşımlar, vol.15, no.4, pp.697-704, 2023 (TRDizin) identifier

  • Publication Type: Article / Review
  • Volume: 15 Issue: 4
  • Publication Date: 2023
  • Doi Number: 10.18863/pgy.1205786
  • Journal Name: Psikiyatride Güncel Yaklaşımlar
  • Journal Indexes: Academic Search Premier, Central & Eastern European Academic Source (CEEAS), Psycinfo, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.697-704
  • Open Archive Collection: AVESIS Open Access Collection
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Autism spectrum disorders (ASD) are neurodevelopmental diseases that manifest themselves at early ages as insufficient social and communicative skills, repetitive sensory-motor behaviors and restricted interests, and peculiar combinations of these traits. Autism prevalence in wealthy nations is currently rising. Due to increasing numbers of diagnosis, studies on the genetic background of autism have gained momentum recently. Especially the research on mitochondrial dysfunction and mammalian target of rapamycin (mTOR) is important in that it might provide a great contribution to the ASD field for new treatment resources. .